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Time to reconsider subcutaneous mastectomy for breast-cancer prevention?

Metcalfe(Kelly A),Semple(John L),Narod(Steve… Lancet Oncol 2005-06-23

...BRCA2, we are identifying more and more women who have an 80% or more lifetime risk of developing breast cancer. Since t...

BRCA2 suppresses cell proliferation via stabilizing MAGE-D1.

Tian(Xin-xia),Rai(Deepak),Li(Jun),Zou(Chaozh… Cancer Res 2005-07-28

...BRCA2-mediated suppression of cell proliferation, indicating that MAGE-D1 is a downstream target of BRCA2 and that BRCA2...

Placental cadherin and the basal epithelial phenotype of BRCA1-related breast c…

Arnes(Jarle B),Brunet(Jean-Sébastien),Stefan… Clin Cancer Res 2005-08-29

...BRCA2 mutation carriers. Descriptive analyses were done followed by survival analyses and a Poisson regression analysis....

c-MYC Asn11Ser is associated with increased risk for familial breast cancer.

Wirtenberger(Michael),Hemminki(Kari),Försti(… Int J Cancer 2005-11-15

...BRCA2 genes. A joint analysis of the Polish and the German study population revealed a 54% increased risk for breast can...

Screening with magnetic resonance imaging and mammography of a UK population at…

Leach(M O),Boggis(C R M),Dixon(A K),Easton(D… Lancet 2005-09-06

...BRCA2, or TP53 mutation. We recruited participants from 22 centres in the UK, and offered the women annual screening wit...

Randomized comparison of group versus individual genetic education and counseli…

Calzone(Kathleen A),Prindiville(Sheila A),Jo… J Clin Oncol 2005-06-24

...BRCA2 mutation testing is necessary for effective utilization of testing in the community. Education and counseling, whe...

CGH analysis of familial non-BRCA1/BRCA2 breast tumors and mutation screening o…

Maguire(Paula),Holmberg(Kerstin),Kost-Alimov… Int J Mol Med 2005-12-15

Mutations in the known predisposing breast cancer genes BRCA1 and BRCA2 account for only a small proportion (<10%) of br...

A comparison of bilateral breast cancers in BRCA carriers.

Weitzel(Jeffrey N),Robson(Mark),Pasini(Barba… Cancer Epidemiol Biomarkers P… 2005-08-30

...BRCA2 mutations. Medical records were reviewed to document the characteristics of each cancer and the treatments receive...

The molecular pathology of hereditary breast cancer: genetic testing and therap…

Honrado(Emiliano),Benítez(Javier),Palacios(J… Mod Pathol 2005-12-16

...BRCA2 loss of heterozygosity (LOH) is found in almost all BRCA1 and BRCA2 carcinomas, respectively. Furthermore, all typ...

[Molecular alterations in breast cancer: clinical implications and new analytic…

Gonçalves(A),Viens(P),Sobol(H),Maraninchi(D)… Rev Med Interne 2005-08-16

...BRCA2, which are associated with a major risk of breast cancer during lifetime, has improved the assessment of the indiv...

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