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TP53 BRCA1 CRISPR single-cell cancer

McClain(Monica R),Palomaki(Glenn E),Nathanso… Genet Med 2005-09-01

Mutations in BRCA1 or BRCA2 genes increase breast cancer risk. Assuring reliability of information about these mutations...

McClain(Monica R),Nathanson(Katherine L),Pal… Genet Med 2005-09-01

Three founder mutations in BRCA1 or BRCA2 genes increase breast cancer risk among Ashkenazi Jewish women. Reported estim...

Tripathi(Manish K),Chaudhuri(Gautam) Biochem Biophys Res Commun 2005-03-28

...BRCA2 gene expression in dividing human breast cells, we transiently knocked down BRCA2 mRNA in HMEC and other cells. Mi...

Wells(D),Bermudez(M G),Steuerwald(N),Thornhi… Hum Reprod 2005-08-31

...BRCA2, ATM, TP53, RB1, MAD2, BUB1, APC and beta-actin) in oocytes and embryos. A full characterization of all genes was ...

Kapma(S),Leschot(N J),Aalfs(C M) Ned Tijdschr Geneeskd 2005-05-16

...BRCA2 was found in family B. In family C, an unclassified variant was found in BRCA1. Further investigations in the fami...

Lu(Huimei),Guo(Xu),Meng(Xiangbing),Liu(Jingm… Mol Cell Biol 2005-03-28

...BRCA2 colocalization in nuclear foci is a hallmark of HRR. BRCA2 has important roles in RAD51 focus formation and HRR of...

Bolufer(Pascual),Munárriz(Blanca),Santaballa… Med Clin (Barc) 2005-05-31

...BRCA2. The mutational spectra vary depending on the study populations and the criteria applied for patient selection. Th...

Perspective on BRCA1.

Newman(B),Liu(E T) Breast Dis 2005-03-21

...BRCA2 was localized to chromosome 13q12-13 two months before the cloning of BRCA1 was reported; less than two years late...

Rimer(B K),Sugarman(J),Winer(E),Bluman(L G),… Breast Dis 2005-03-21

While the cloning of BRCA1 and BRCA2 in 1994 and 1995 engendered great enthusiasm from cancer patients, their families a...

Berry(D A),Parmigiani(G) Breast Dis 2005-03-21

Tests for the presence of mutations of genes BRCA1 and BRCA2 are increasingly available. Genetic testing creates dilemma...

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