...BRCA2 among Asian populations. We investigated the distribution of BRCA1 and BRCA2 germ-line mutations and polymorphisms...
The tumor suppressor BRCA2 plays an essential role in the repair of double-strand DNA breaks by regulating the action of...
...BRCA2 gene. Since carriers of germline BRCA2 gene mutations have an increased risk of developing pancreatic cancer, the ...
The BCCIP alpha protein was identified as a BRCA2 and CDKN1A (p21, or p21(Waf1/Cip1)) Interacting Protein. It binds to a...
...BRCA2, ATM gene, PTEN and p53. Several other less frequently occurring predisposition genes such as the androgen recepto...
...BRCA2 mutation carriers (Predisposed OSE, POSE) and from 26 women without such risk (Non Predisposed OSE, NPOSE). Number...
Women with a germline BRCA1 or BRCA2 mutation have a significantly increased risk of developing ovarian cancer compared ...
...BRCA2). Mutations in the FANCA gene are the most prevalent, accounting for two-thirds of FA cases. Affected individuals ...
Biallelic mutations in BRCA2/FANCD1 were recently recognized as a rare cause of Fanconi anemia (FA). Using immunodetecti...
...BRCA2, but is also attributable to another gene in this region. There is strong indication of a new tumor suppressor gen...
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