Germline mutations in BRCA1 and BRCA2 account for majority of hereditary breast and ovarian cancer. The complete coding ...
...BRCA2 mutations, FA, and early onset acute leukemia. Leukemia occurred at a median of 2.2 years of age in the BRCA2 pati...
...BRCA2, and WT1. We examine protein variants caused by nonsynonymous single-nucleotide polymorphisms in a set of clinical...
...BRCA2 genes. We found 12 distinct variants in 30 unrelated patients (5.81%), including 5 that are novel and an additiona...
...BRCA2 mutation carriers and 1,097 age-matched controls with a mutation in the same gene but without breast cancer. There...
...BRCA2 SNP sites.
...BRCA2 genes, which are responsible for almost three-quarters of those hereditary tumours.
...BRCA2 or the RAD51 paralogues. It is known that BRCA2 interacts directly with RAD51 through a series of degenerative mot...
...BRCA2) and retinoblastoma (RB1) genes, is frequently rearranged in B-cell chronic lymphocytic leukaemia, and contains th...
...BRCA2 genes has explained some of the genetic determinants of breast cancer risk, but these genes alone do not explain a...
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