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A paradigm for class prediction using gene expression profiles.

Radmacher(Michael D),McShane(Lisa M),Simon(R… J Comput Biol 2003-01-28

...BRCA2 mutations. In both cases, the accuracy of class prediction was statistically significant when compared to the accu...

BRCA2 monoclonal antibodies react with differentiating epithelium.

Gilliam(Lisa K),Lobenhofer(Edward K),Greer(P… Hybrid Hybridomics 2003-02-05

...BRCA2 gene has previously been suggested to play a role in proliferation and DNA repair. Germline mutations in the BRCA2...

The pathology of inherited breast cancer.

Armes(Jane E),Venter(Deon J) Pathology 2003-03-06

...BRCA2. Since the discovery of these genes, studies have been performed in which the pathological characteristics of fami...

Genomic organization and expression of the mouse Brca2 gene.

Callens(Nathalie),Dumont(Martine),Begue(Agnè… Mamm Genome 2003-01-30

A mutation of the Brca2 gene product is responsible for a large proportion of the inherited breast cancers. Here, we hav...

Gene selection: a Bayesian variable selection approach.

Lee(Kyeong Eun),Sha(Naijun),Dougherty(Edward… Bioinformatics 2003-07-22

...BRCA2 are associated with a hereditary disposition to breast cancer, and the method is used to identify a set of signifi...

Genetic basis of Fanconi anemia.

Bagby(Grover C) Curr Opin Hematol 2003-07-02

...BRCA2, are hypomorphic and lead to FA-D1 and possibly FA-B. Because the Fanconi anemia alleles of BRCA2 fail to bind to ...

Homologous repair of DNA damage and tumorigenesis: the BRCA connection.

Jasin(Maria) Oncogene 2003-01-15

...BRCA2, show defects in DNA repair by homologous recombination, implicating this repair pathway in protecting individuals...

The cancer connection: BRCA1 and BRCA2 tumor suppression in mice and humans.

Moynahan(Mary Ellen) Oncogene 2003-01-15

...Brca2 alleles and cre-mediated tissue-specific deletions for Brca1 and Brca2 have been generated. Mice deficient for eit...

Breast cancer genetics in African Americans.

Olopade(Olufunmilayo I),Fackenthal(James D),… Cancer 2003-01-15

An overview of the state of genetic testing for BRCA1 and BRCA2 genes was presented at the Summit Meeting on Breast Canc...

[Frequency of the 185delAG mutation in the BRCA1 gene in Chilean healthy women …

Jara(Lilian),Ampuero(Sandra),Seccia(Lorena),… Rev Med Chil 2003-03-03

...BRCA2 are two major hereditary breast cancer susceptibility genes. Mutations in these genes are associated to inherited ...

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