...BRCA2. Among carriers of the BRCA1 mutation, mean age at diagnosis in the mothers' generation (44 +/- 10.18 years) did n...
...BRCA2. As these three founder mutations are common in the Ashkenazi Jewish population ( approximately 2.5%) and can easi...
...BRCA2), and if so, to opt for frequent surveillance and/or prophylactic surgery (bilateral mastectomy and/or oophorectom...
...BRCA2 exon 11 showed apparent homozygosity for the 6174delT mutation in two healthy sisters. Subsequent sequencing of an...
...BRCA2 and RB1, which map to chromosome 13, was examined by reverse transcription- polymerase chain reaction analysis. BR...
...BRCA2 carriers (67% vs 52%; P =.004).,In these families with breast and/or ovarian cancer, mutations in BRCA1 but not BR...
...BRCA2 genes by exclusion of common BRCA1/BRCA2 alleles in a given family by using polymorphic dinucleotide markers. The ...
...BRCA2 sequence variants. Predictions on the BRCA1/BRCA2 protein functions lead to the identification of 11 novel deleter...
...BRCA2, predisposes individuals to breast and ovarian cancers. Current progress in determining the function of these gene...
In order to identify the spectrum of BRCA2 mutations in African Americans, breast or ovarian cancer patients from 74 ind...
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