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TP53 BRCA1 CRISPR single-cell cancer

Wang(Chiang),McCarty(Ida M),Balazs(Louisa),L… Biochem Biophys Res Commun 2002-08-09

...BRCA2, predisposes humans to breast and ovarian cancers. Inherited mutations in the BRCA2 gene are also known to cause s...

Vahteristo(Pia),Bartkova(Jirina),Eerola(Hann… Am J Hum Genet 2002-08-20

...BRCA2 mutations confirmed a significantly elevated frequency of 1100delC (28/507 [5.5%]; OR 4.2; 95% CI 2.4-7.2; P=.0002...

Hayashi(Naoko),Egami(Hiroshi),Ogawa(Michio) Nihon Geka Gakkai Zasshi 2002-07-16

...BRCA2, coupled with the activation of oncogenes such as K-ras, are a few of the mutations that trigger the growth of can...

Sinclair(Colleen S),Adem(Camilo),Naderi(Ali)… Cancer Res 2002-08-08

...BRCA2 mutant breast tumors, 15 breast tumors from high-risk patients with no BRCA1 or BRCA2 mutations, and 62 matched sp...

Jazaeri(Amir A),Yee(Cindy J),Sotiriou(Christ… J Natl Cancer Inst 2002-07-25

...BRCA2-like," suggesting that BRCA1-related and BRCA2-related pathways are also involved in sporadic ovarian cancers. Fif...

Murphy(Kathleen M),Brune(Kieran A),Griffin(C… Cancer Res 2002-08-08

...BRCA2 mutations and identify germ-line BRCA2 mutations as the most common inherited genetic alteration yet identified in...

Ben David(Y),Chetrit(A),Hirsh-Yechezkel(G),F… J Clin Oncol 2002-03-19

...BRCA2 carriers and noncarriers among the women with invasive ovarian cancer (median survival, 53.4 months v. 37.8 months...

Schwartz(Marc D),Peshkin(Beth N),Hughes(Chan… J Clin Oncol 2002-03-19

...BRCA2 genetic testing, little is known about the psychologic impact of such testing in the clinical setting. The objecti...

Liu(Yilun),West(Stephen C) Breast Cancer Res 2002-12-27

Individuals carrying BRCA mutations are predisposed to breast cancer. The BRCA1 and BRCA2 proteins are required for homo...

Basham(Victoria M),Lipscombe(Julian M),Ward(… Breast Cancer Res 2002-12-27

...BRCA2. Allowing for a mutation detection sensitivity frequency of 70%, the carrier frequency for BRCA2 mutations was 8% ...

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