Carriers of one mutant allele of either BRCA1 or BRCA2 are at risk for somatic loss of the second wild-type allele, lead...
...BRCA2-containing complex. Biochemical analysis revealed the presence of a smaller core-BRAF35 complex devoid of BRCA2. H...
...BRCA2 in the homologous recombination repair (HRR) of double-strand breaks in DNA implicates this pathway in the suppres...
...BRCA2 mutations identified during a six-year period were offered enrollment in a prospective follow-up study. A total of...
...BRCA2 mutations are limited. We investigated whether this procedure reduces the risk of cancers of the coelomic epitheli...
...BRCA2, which from a population perspective are much more important than TP53. Other rarer genes have subsequently been i...
...BRCA2. Genetic testing for BRCA1 and BRCA2 is highly sensitive, missing an estimated 15% of mutations. In the population...
...BRCA2 genes or had family history suggestive for ovarian and breast cancer susceptibility.,Thirty women with either a do...
...BRCA2 gene mutations. These results suggest that genetic factors account for the excess in ovarian cancer that occurs in...
...BRCA2 mutations, six in BRCA1, and seven in BRCA2. We have further studied the non-familial ovarian cancer cases to dete...
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