...BRCA2, E-cadherin, p53, BRCA1, and DPC4 loci. Immunohistochemical staining with anti-Fhit antibody was performed in 7 Kr...
...BRCA2 in the homologous recombination repair (HRR) of double-strand breaks in DNA implicates this pathway in the suppres...
...BRCA2 mutations identified during a six-year period were offered enrollment in a prospective follow-up study. A total of...
...BRCA2 mutations are limited. We investigated whether this procedure reduces the risk of cancers of the coelomic epitheli...
...BRCA2 genes. Brca1 and Brca2 proteins are both involved in the cellular defence against DNA damage, although the precise...
Carriers of one mutant allele of either BRCA1 or BRCA2 are at risk for somatic loss of the second wild-type allele, lead...
...BRCA2, which from a population perspective are much more important than TP53. Other rarer genes have subsequently been i...
...BRCA2, have been identified. To date, several hundred pathogenic mutations in these two genes have been published or rep...
Mutations in BRCA1 and BRCA2 confer a high risk of breast and ovarian cancer, but account for only a small fraction of b...
...BRCA2 gene is unknown.,In a Washington DC community-based study conducted in 1996, we tested 5318 Ashkenazi Jews for thr...
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