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Preferential loss of Fhit expression in signet-ring cell and Krukenberg subtype…

Chang(Yu-Ting),Wu(Ming-Shiang),Chang(Chee-Je… Lab Invest 2002-09-26

...BRCA2, E-cadherin, p53, BRCA1, and DPC4 loci. Immunohistochemical staining with anti-Fhit antibody was performed in 7 Kr...

A potential role for the XRCC2 R188H polymorphic site in DNA-damage repair and …

Rafii(Saeed),O'Regan(Paul),Xinarianos(George… Hum Mol Genet 2002-08-30

...BRCA2 in the homologous recombination repair (HRR) of double-strand breaks in DNA implicates this pathway in the suppres...

Risk-reducing salpingo-oophorectomy in women with a BRCA1 or BRCA2 mutation.

Kauff(Noah D),Satagopan(Jaya M),Robson(Mark … N Engl J Med 2002-05-28

...BRCA2 mutations identified during a six-year period were offered enrollment in a prospective follow-up study. A total of...

Prophylactic oophorectomy in carriers of BRCA1 or BRCA2 mutations.

Rebbeck(Timothy R),Lynch(Henry T),Neuhausen(… N Engl J Med 2002-05-28

...BRCA2 mutations are limited. We investigated whether this procedure reduces the risk of cancers of the coelomic epitheli...

BRCA1 and BRCA2 heterozygosity and repair of X-ray-induced DNA damage.

Nieuwenhuis(B),Van Assen-Bolt(A J),Van Waard… Int J Radiat Biol 2002-06-14

...BRCA2 genes. Brca1 and Brca2 proteins are both involved in the cellular defence against DNA damage, although the precise...

Selective loss of heterozygosity in multiple breast cancers from a carrier of m…

Bell(Daphne W),Erban(John),Sgroi(Dennis C),H… Cancer Res 2002-07-10

Carriers of one mutant allele of either BRCA1 or BRCA2 are at risk for somatic loss of the second wild-type allele, lead...

The contribution of inherited factors to the clinicopathological features and b…

Foulkes(W D),Rosenblatt(J),Chappuis(P O) J Mammary Gland Biol Neoplasia 2002-06-17

...BRCA2, which from a population perspective are much more important than TP53. Other rarer genes have subsequently been i...

Analysis of BRCA1 and BRCA2 in breast and breast/ovarian cancer families shows …

Vega(A),Torres(M),Martínez(J I),Ruiz-Ponte(C… Ann Hum Genet 2002-10-01

...BRCA2, have been identified. To date, several hundred pathogenic mutations in these two genes have been published or rep...

Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in nonca…

Meijers-Heijboer(Hanne),van den Ouweland(Ans… Nat Genet 2002-05-28

Mutations in BRCA1 and BRCA2 confer a high risk of breast and ovarian cancer, but account for only a small fraction of b...

Breast cancer risk in Ashkenazi BRCA1/2 mutation carriers: effects of reproduct…

Hartge(Patricia),Chatterjee(Nilanjan),Wachol… Epidemiology 2002-05-23

...BRCA2 gene is unknown.,In a Washington DC community-based study conducted in 1996, we tested 5318 Ashkenazi Jews for thr...

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