...PMS2 and MSH6 immunohistochemistry. p53 overexpression was associated with younger patients, left-sided tumors, nodal me...
...PMS2 or MLH1 in seven patients (31.8%). Germline mutation testing confirmed Lynch syndrome in 16 (67%) patients. ICI mon...
...PMS2 dual loss pattern. A novel germline variant APC c.3799dup was identified in all affected family members but was abs...
...PMS2 gene (PMS2:NM_000535:exon11:c.1847T>C:p.V616A and PMS2:NM_000535:exon14:c.2444C>T:p.S815L) were considered variants...
...PMS2). Statistical analysis was performed to determine correlations with clinicopathological variables such as age, gend...
...PMS2 are more strongly associated with ILC - to varying degrees. [p < 0.001]. Additionally, ILC tumors kept several char...
...PMS2) and HRR (BRCA1 and BRCA2, among others) variants, comparing with an institutional cohort of MMR carriers (n = 35; ...
...PMS2 subgroups. No statistically significant differences in PFS were observed between gene groups. Performance status ≥ ...
...PMS2 expression. Pembrolizumab combined with capecitabine and oxaliplatin (CAPOX) was initiated as fifth-line therapy, r...
...PMS2). Their DOG1, MUC2, MUC5AC, MUC6, CDX2, keratin-20, and keratin-7 immunoprofiles were then compared with histopatho...
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