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Li(NM),Cheng(HP),Zhou(P),Li(XH) Zhonghua Zhong Liu Za Zhi 2026-07-23

...BRCA2 mutation and was HRD score-positive. TMB-H status was significantly associated with HRD positivity (P＜0.05), where...

Tooming(M),Rekker(K),Toome(K),Roht(L),Laid... Front Genet None

...BRCA2, and other cancer-associated genes plays a critical role in the diagnosis, prognosis, and management of breast and...

Cruellas(M),Rodriguez-Hernandez(A),Carità(... ESMO Open 2026-08-00

...BRCA2 tumors. BRCA2 PVs were independently associated with poorer outcomes to first-line CDK4/6i plus ET in HR-positive/...

Michels(DCR),Singh(A),Patel(M),Rasheed(B),... Am J Physiol Heart Circ Phy... 2026-08-01

...BRCA2 protects against atherogenesis under stress conditions. Endothelial-specific BRCA2 knockdown mice (BRCA2EC-KO) wer...

Domènech(H),Simonetti(S),Romero-Lozano(P),... NPJ Precis Oncol 2026-07-11

...BRCA2 reversion mutations in >30% of post-PARPi mBC samples, which were associated with poor response to subsequent plat...

Karimaghaie(T),Fasano(G),Lopez(S),Min(S),K... Gynecol Oncol Rep 2026-08-00

Pathogenic variants (PVs) in the BRCA1 and BRCA2 ( BRCA1/2) genes increase lifetime risk of several cancers including br...

Macedo(GS),Schuch(JB),Cadore(NA),Cerveira ... Genet Med Open None

...BRCA2, and FANCA. Even with the low success rate of tumor samples, our data demonstrated that most loss-of-function vari...

Godino(L),Innella(G),Di Palo(C),Bono(GR),T... Eur J Surg Oncol 2026-09-00

...BRCA2 pathogenic variants face a substantially increased risk of breast cancer and may choose between risk-reducing mast...

Gu(W),Khan(NU),Lei(H),Fu(J),Xu(C),Chen(X),... Front Oncol None

...BRCA2 (BRCA1/2) variant landscape specifically in high-risk, clinically referred populations remains poorly characterize...

Zeal(JL),Woodcock(MG),Chen(KY),Stein(JN) Front Oncol None

...BRCA2 deep deletion. After progressing on multiple lines of systemic therapies, her widely metastatic disease has been c...