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Full-exon pyrosequencing screening of BRCA germline mutations in Mexican women …

Vaca-Paniagua(Felipe),Alvarez-Gomez(Rosa Mar… PLoS One 2012-09-27

...BRCA2 (breast cancer early onset 1 and 2), which also predispose to other cancers. Despite the outstanding relevance of ...

A variant of the breast cancer type 2 susceptibility protein (BRC) repeat is es…

Islam(M Nurul),Paquet(Nicolas),Fox(David),Dr… J Biol Chem 2012-10-09

The BRC repeat is a structural motif in the tumor suppressor BRCA2 (breast cancer type 2 susceptibility protein), which ...

BRCA2 mutations and triple-negative breast cancer.

Meyer(Peter),Landgraf(Katharina),Högel(Bernh… PLoS One 2012-10-29

...BRCA2 was either not analyzed or showed much lower mutation frequencies. Therefore, we screened a group of TNBC patients...

Hyperbaric oxygen treatment for skin flap necrosis after a mastectomy: a case s…

Mermans(Joline F),Tuinder(Stefania),von Meye… Undersea Hyperb Med 2012-06-14

...BRCA2 mutation gene was successfully treated with hyperbaric oxygen therapy.

RNF4, a SUMO-targeted ubiquitin E3 ligase, promotes DNA double-strand break rep…

Galanty(Yaron),Belotserkovskaya(Rimma),Coate… Genes Dev 2012-08-02

...BRCA2 and RAD51 on resected DNA. Consistent with previous data showing that RNF4 targets proteins to the proteasome, we ...

Association of PHB 1630 C>T and MTHFR 677 C>T polymorphisms with breast and ova…

Jakubowska(A),Rozkrut(D),Antoniou(A),Hamann(… Br J Cancer 2012-08-07

...BRCA2 mutation carriers, and 6211 BRCA1 and 2902 BRCA2 carriers from the Consortium of Investigators of Modifiers of BRC...

Familial pancreatic cancer--current knowledge.

Bartsch(Detlef K),Gress(Thomas M),Langer(Pet… Nat Rev Gastroenterol Hepatol 2012-12-13

...BRCA2, PALB2 and ATM are causative in some FPC families. Expert consensus conferences considered it appropriate to scree...

Characteristics and spectrum of BRCA1 and BRCA2 mutations in 3,922 Korean patie…

Kim(Haeyoung),Cho(Dae-Yeon),Choi(Doo Ho),Cho… Breast Cancer Res Treat 2012-12-13

...BRCA2. The majority (134 of 150) of the distinct mutations resulted in premature termination codon of the BRCA1/2 transl...

BRCA2 variants and cardiovascular disease in a multi-ethnic study.

Zbuk(Kevin),Xie(Changchun),Young(Robin),Heyd… BMC Med Genet 2012-11-06

...BRCA2 variants and CVD was evaluated. 15 SNPs in BRCA2 with minor allele frequencies (MAF) > 0.01 had been previously ge...

To the rescue: the Fanconi anemia genome stability pathway salvages replication…

Moldovan(George-Lucian),D'Andrea(Alan D) Cancer Cell 2012-09-17

...BRCA2 tumor suppressor pathways cooperate to protect stalled replication forks from degradation.

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