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Minding the gap: the underground functions of BRCA1 and BRCA2 at stalled replic…

Nagaraju(Ganesh),Scully(Ralph) DNA Repair (Amst) 2007-10-04

The hereditary breast and ovarian cancer predisposition genes, BRCA1 and BRCA2, participate in the repair of DNA double ...

FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage…

Ling(Chen),Ishiai(Masamichi),Ali(Abdullah Ma… EMBO J 2007-10-04

...BRCA2. The complex consists of eight FA proteins, including a ubiquitin ligase (FANCL) and a DNA translocase (FANCM), an...

Concomitant BRCA1 and BRCA2 gene mutations in an Ashkenazi Jewish woman with pr…

Spannuth(Whitney A),Thaker(Premal H),Sood(An… Am J Obstet Gynecol 2007-04-20

...BRCA2 mutations (BRCA1 5382insC and BRCA2 6174delT). While these mutations are known to occur individually in Ashkenazi ...

Electron microscopy reconstructions of DNA repair complexes.

Llorca(Oscar) Curr Opin Struct Biol 2007-06-27

...Brca2 were found to regulate homologous recombination.

Heteroduplex analysis by capillary array electrophoresis for rapid mutation det…

Velasco(Eladio),Infante(Mar),Durán(Mercedes)… Nat Protoc 2007-06-29

...BRCA2 genes from two patients (approximately 25 kb each) to be scanned in a single run of a 16-capillary sequencer, and ...

Morphological features of TMPRSS2-ERG gene fusion prostate cancer.

Mosquera(J-M),Perner(S),Demichelis(F),Kim(R)… J Pathol 2007-06-18

...BRCA2 mutations. The biological effect of TMPRSS2-ERG overexpression may drive pathways that favour these common morphol...

A case of loss of heterozygosity in the BRCA2 gene of a borderline ovarian tumo…

Verbruggen(M B),Zweemer(R P),Piek(J M J),van… Int J Gynecol Cancer 2007-12-14

...BRCA2 mutation carrier could be attributed to this mutation, in which case BOT should be added to the BRCA2 related tumo...

Germline mutations of TP53 and BRCA2 genes in breast cancer/sarcoma families.

Manoukian(Siranoush),Peissel(Bernard),Pensot… Eur J Cancer 2007-05-01

...BRCA2 genes. Families were classified according to their conformity to the criteria defining the Li-Fraumeni syndrome (L...

Literature based discovery of gene clusters using phylogenetic methods.

Sarkar(Indra Neil),Agrawal(Abha) AMIA Annu Symp Proc 2007-09-28

...BRCA2, we examine the relevance of the clustered genes proposed by the different clustering methods based on the number ...

Lifestyle behaviors in women with a BRCA1 or BRCA2 genetic mutation: an explora…

Spector(Denise) Cancer Nurs 2007-02-07

...BRCA2 genetic mutations. The aims of this qualitative pilot study were to explore current lifestyle practices among thes...

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