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Lower level of BRCA2 protein in heterozygous mutation carriers is correlated wi…

Arnold(Katrin),Kim(Min-Kyoung),Frerk(Katrin)… Cancer Lett 2006-12-06

...BRCA2+/- cells showed lower amounts of the full-length BRCA2 protein compared to BRCA2+/+ cells. The kinetics of gamma-H...

Establishment of three human breast epithelial cell lines derived from carriers…

Rubner Fridriksdottir(Agla J),Gudjonsson(Tho… In Vitro Cell Dev Biol Anim 2006-10-05

...BRCA2-999del5-2T and BRCA2-999del5-2N, respectively. In addition, one cell line was derived from cancer-associated norma...

Cancer risk assessment at the atomic level.

Monteiro(Alvaro N A),Couch(Fergus J) Cancer Res 2006-04-13

...BRCA2 have not only shed light on the biology of these proteins but have also raised hopes that these data could eventua...

Genetic and histopathologic evaluation of BRCA1 and BRCA2 DNA sequence variants…

Chenevix-Trench(Georgia),Healey(Sue),Lakhani… Cancer Res 2006-04-13

...BRCA2 carriers undergo inactivation of the wild-type allele by loss of heterozygosity. We examined 10 BRCA1 and 15 BRCA2...

Male breast cancer.

Fentiman(Ian S),Fourquet(Alain),Hortobagyi(G… Lancet 2006-03-02

...BRCA2 rather than BRCA1 mutations. Occupational risks include high temperature environments and exhaust fumes, but elect...

The common variant N372H in BRCA2 gene may be associated with idiopathic male i…

Zhoucun(A),Zhang(Sizhong),Yang(Yuan),Ma(Yong… Eur J Obstet Gynecol Reprod B… 2006-02-17

...BRCA2) and the idiopathic male infertility with azoospermia or severe oligozoospermia.,The study included 240 infertile ...

[Hereditary predispositions to gynaecological cancers].

Coupier(I),Pujol(P) Gynecol Obstet Fertil 2006-01-06

...BRCA2) and family cases of colon cancer, endometrial cancer and ovarian cancer (Lynch syndrome or HNPCC) (genes hMLH1, h...

Localization of breast cancer susceptibility loci by genome-wide SNP linkage di…

Ellis(Nathan A),Kirchhoff(Tomas),Mitra(Nandi… Genet Epidemiol 2006-04-03

...BRCA2*6174delT founder mutation; a "field" set of 19 breast cancer cases from male breast cancer kindreds, which simulat...

DSS1 is required for the stability of BRCA2.

Li(J),Zou(C),Bai(Y),Wazer(D E),Band(V),Gao(Q) Oncogene 2006-03-28

...BRCA2 in mammalian cells. We found that essentially all BRCA2 in human cell lines is associated with DSS1. Importantly, ...

Analysis of genetic variations in the exon 27 region of the canine BRCA2 locus.

Yoshikawa(Yasunaga),Morimatsu(Masami),Ochiai… J Vet Med Sci 2006-05-05

...BRCA2 gene encodes a large nuclear protein that is involved in DNA repair, and mutations in the human BRCA2 confer an in...

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