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[The structural reorganization of chromatin as a process of its self-organizati…

Spitkovskiĭ(D M),Veĭko(N N),Moiseeva(O S),Er… Radiats Biol Radioecol 2006-01-23

...BRCA2 genes mutations the chromosome loci transference could not be induced by the X-radiation, but it could be induced ...

Solution structure of the human ubiquitin-specific protease 15 DUSP domain.

de Jong(Rob N),Ab(Eiso),Diercks(Tammo),Truff… J Biol Chem 2006-05-04

...BRCA2. We describe the NMR solution structure of the DUSP domain of human USP15, recently implicated in COP9 (constituti...

Estradiol and its metabolites 4-hydroxyestradiol and 2-hydroxyestradiol induce …

Fernandez(Sandra V),Russo(Irma H),Russo(Jose) Int J Cancer 2006-04-18

...BRCA2. Cells treated with E2 or 4-OHE2 at doses of 0.007 and 70 nM and 2-OHE2 only at a higher dose (3.6 microM) showed ...

Efficient deletion of normal Brca2-deficient intestinal epithelium by poly(ADP-…

Hay(Trevor),Jenkins(Helen),Sansom(Owen J),Ma… Cancer Res 2006-01-18

...Brca2 allele has not taken place. In this study, we have treated Brca2-deficient small intestine with a potent small-mol...

Genomic instability and cancer: networks involved in response to DNA damage.

Eyfjord(Jorunn Erla),Bodvarsdottir(Sigridur … Mutat Res 2006-08-11

...BRCA2. Chromosomal instability is a common feature of many human cancers and most of the instability syndromes, characte...

Analysis of albumin-associated peptides and proteins from ovarian cancer patien…

Lowenthal(Mark S),Mehta(Arpita I),Frogale(Kr… Clin Chem 2006-01-11

...BRCA2, a 390-kDa low-abundance nuclear protein linked to cancer susceptibility, was represented in sera as a series of s...

Factors increasing local recurrence in breast-conserving surgery.

Fatouros(Michael),Roukos(Dimitrios H),Arampa… Expert Rev Anticancer Ther 2006-02-07

...BRCA2 mutations should be informed about the increased risk of contralateral breast cancer and ipsilateral failure after...

Absence of specific cell killing of the BRCA2-deficient human cancer cell line …

Gallmeier(Eike),Kern(Scott E) Cancer Biol Ther 2006-04-20

...BRCA2 6174delT frameshift mutation accompanied by loss of the second allele. The severe impact of this mutation on BRCA2...

Communication and decision-making about seeking inherited cancer risk informati…

Mellon(Suzanne),Berry-Bobovski(Lisa),Gold(Ro… Psychooncology 2006-08-10

...BRCA2 have led to new options in genetic risk assessment for families with histories of breast and ovarian cancer. Howev...

Poly(ADP-ribose) polymerase (PARP-1) in homologous recombination and as a targe…

Helleday(Thomas),Bryant(Helen E),Schultz(Nik… Cell Cycle 2006-06-12

...BRCA2 tumors.

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