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Identification of novel BRCA founder mutations in Middle Eastern breast cance...

Bu(Rong),Siraj(Abdul K),Al-Obaisi(Khadija ... Int J Cancer 0000-00-00

...BRCA2 mutations in different populations. The prevalence and effect of BRCA 1 and BRCA 2 mutations in Middle Eastern pop...

Oncotype-DX recurrence score distribution in breast cancer patients with BRCA...

Lewin(R),Sulkes(A),Shochat(T),Tsoref(D),Ri... Breast Cancer Res Treat 0000-00-00

...BRCA2). The GP included 1020 patients. Compared to the GP, BRCA1 patients were younger, had higher rate of grade three t...

Implications of High Rates of Metastatic Prostate Cancer in BRCA2 Mutation Ca...

Gleicher(Stephanie),Kauffman(Eric C),Kotul... Prostate 0000-00-00

...BRCA2 gene mutations (BRCA2mut) have more aggressive prostate cancer. Analysis of all reported germline BRCA2mut prostat...

BRCA1-2 diagnostic workflow from next-generation sequencing technologies to v...

Pilato(Brunella),Pinto(Rosamaria),De Summa... Genes Chromosomes Cancer 0000-00-00

The BRCA1-BRCA2 genes predispose to hereditary breast and ovarian cancer, and the germline and mutational status of thes...

Dynamics of chromosomal aberrations, induction of apoptosis, BRCA2 degradatio...

Bergs(Judith W J),Oei(Arlene L),Ten Cate(R... Int J Mol Med 0000-00-00

Hyperthermia can transiently degrade BRCA2 and thereby inhibit the homologous recombination pathway. Induced DNA-double ...

RANKL/RANK control Brca1 mutation-driven mammary tumors.

Sigl(Verena),Owusu-Boaitey(Kwadwo),Joshi(P... Cell Res 0000-00-00

...BRCA2 genes markedly increase the risk for the development of breast cancer. Here, using two different mouse models, we ...

How Far Do We Go With Genetic Evaluation? Gene, Panel, and Tumor Testing.

Lynce(Filipa),Isaacs(Claudine) Am Soc Clin Oncol Educ Book 0000-00-00

...BRCA2 for hereditary breast and ovarian cancer or mismatch repair genes for Lynch syndrome). The decision regarding whic...

Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Color...

Fehringer(Gordon),Kraft(Peter),Pharoah(Pau... Cancer Res 0000-00-00

...BRCA2 locus with lung and serous ovarian cancer. This is the largest study to date examining pleiotropy across multiple ...

Association of Common Susceptibility Variants of Pancreatic Cancer in Higher-...

Childs(Erica J),Chaffee(Kari G),Gallinger(... Cancer Epidemiol Biomarkers... 0000-00-00

...BRCA2, PALB2, ATM, p16/CDKN2A or DNA mismatch repair genes), common genetic variants may also be involved. In a high-ris...

A Comparison of Fresh Frozen vs. Formalin-Fixed, Paraffin-Embedded Specimens ...

Lüder Ripoli(Florenza),Mohr(Annika),Conrad... Int J Mol Sci 0000-00-00

...BRCA2; BRCA1; HMGA2; and Her2) were analyzed via branched-DNA assay (b-DNA). ACTB, GAPDH, and HPRT1 were used as data no...

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