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TP53 BRCA1 CRISPR single-cell cancer

Pericay(C),Brunet(J),Díez(O),Sanz(J),Cortès(… Breast 2004-02-26

...BRCA2) and sequencing (the rest of exons). At diagnosis the mean age was 37 years (28-54). Only 3/17 patients presented ...

Altaha(Ramin),Reed(Eddie),Abraham(Jame) W V Med J 2004-03-08

...BRCA2 mutations (BRCA1/2 mutation) have a 65% to 85% cumulative lifetime risk of developing invasive breast cancer and a...

Liede(Alexander),Karlan(Beth Y),Narod(Steven… J Clin Oncol 2004-03-02

...BRCA2 is the more important gene for men. The spectrum of cancers is wide for BRCA2 and some studies report that the ove...

Wong(Alice S T),Auersperg(Nelly) Reprod Biol Endocrinol 2004-09-08

...BRCA2, provide a background to facilitate understanding of the early changes in ovarian carcinogenesis. This overview is...

Dong(Yuanshu),Hakimi(Mohamed-Ali),Chen(Xiaow… Mol Cell 2004-01-05

...BRCA2, and RAD51. BRCC not only displays increased association with p53 following DNA damage but also ubiquitinates p53 ...

Haber(Daniel A) Cell 2004-01-14

...BRCA2 inactivation. The implications for BRCA2 function are discussed.

Hughes-Davies(Luke),Huntsman(David),Ruas(Mar… Cell 2004-01-14

...BRCA2 within a region (exon 3) deleted in cancer. EMSY is capable of silencing the activation potential of BRCA2 exon 3,...

Sharan(Shyam K),Pyle(April),Coppola(Vincenzo… Development 2004-03-03

...Brca2 in gametogenesis has been obscure because of embryonic lethality of the knockout mice. We generated Brca2-null mic...

Meng(Xiangbing),Yuan(Yuan),Maestas(Adrian),S… J Biol Chem 2004-03-30

...BRCA2, and lack of filamin-A expression results in increased cellular sensitivity to several DNA damaging agents in mela...

Fisher(T J),Kirk(J),Hopper(J L),Godding(R),B… Breast 2004-01-06

...BRCA2. The authors developed a short questionnaire to categorize risk according to breast cancer history in close relati...

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